mouse anti centrin 3 (Santa Cruz Biotechnology)
Structured Review
Mouse Anti Centrin 3, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 8 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+anti+centrin+3/Centrin-3+Antibody/pmc12480466-291-15-18
Average 93 stars, based on 8 article reviews
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Immunofluorescence:Article Title: Asterless is a scaffold for the onset of centriole assembly. Article Snippet: Centrioles are found in the centrosome core and, as basal bodies, at the base of cilia and flagella.. Centriole assembly and duplication is controlled by Polo-like-kinase 4 (Plk4): these processes fail if Plk4 is downregulated and are promoted by Plk4 overexpression.. Here we show that the centriolar protein Asterless (Asl; human orthologue CEP152) provides a conserved molecular platform, the amino terminus of which interacts with the cryptic Polo box of Plk4 whereas the carboxy terminus interacts with the centriolar protein Sas-4 (CPAP in humans). Western Blot:Article Title: Asterless is a scaffold for the onset of centriole assembly. Article Snippet: Centrioles are found in the centrosome core and, as basal bodies, at the base of cilia and flagella.. Centriole assembly and duplication is controlled by Polo-like-kinase 4 (Plk4): these processes fail if Plk4 is downregulated and are promoted by Plk4 overexpression.. Here we show that the centriolar protein Asterless (Asl; human orthologue CEP152) provides a conserved molecular platform, the amino terminus of which interacts with the cryptic Polo box of Plk4 whereas the carboxy terminus interacts with the centriolar protein Sas-4 (CPAP in humans). |
